In Vitro Technologies

The PartoSure Test is a rapid, non-invasive strip test for the detection of placental alpha microglobulin-1 (PAMG-1), in patients presented with signs and symptoms of preterm labour. PartoSure’s unique features include:

High Positive (PPV) and Negative Predictive Value (NPV)
Usable shortly after vaginal exam
Speculum examination optional
Results in 5 minutes or less
No special equipment or training needed
Wide gestational age range from 20 to 37 weeks

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Accurately assessing the risk of preterm birth is a difficult diagnosis with significant implications. Clinical evaluation alone is limited in its ability to predict imminent delivery among patients with signs of threatened preterm labor (PTL).

In patients presenting with signs and symptoms of threatened PTL, 28% may be admitted to the hospital (1).
Studies show 7–20% of patients admitted deliver within 7 days (2–4).
Unnecessary admissions cost $20.3K/case on average (5).

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A more accurate assessment to identify those truly at risk of preterm labor is needed

The PartoSure Test is a rapid, qualitative test for detecting the presence of placental alpha microglobulin 1 (PAMG-1) in cervicovaginal secretions in pregnant women with signs and symptoms of early preterm labor (6).

Simple steps, rapid results

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Results in 5 minutes with our 4-step testing procedure (6)

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Reducing unnecessary interventions may lead to decreased costs

Published studies suggest a lower rate of false positive test results and associated higher PPVs, such as those seen in the PartoSure Test, may contribute to:

• Decreasing unnecessary admissions and acute interventions
• Reducing the length of stay of high risk patients
• Minimizing unnecessary patient transfers

The average US birthing hospital has approximately 1,200 births annually and PTL tests may be used on up to 300 of these patients (7).

Up to 37 patients may avoid unnecessary intervention annually, which could result in savings of approximately $750K (5, 8).

PartoSure Chart 1

References:
1. Grobman, W.A. et al. (2004) Am. J. Obstet Gynecol. 191, 235.
2. Sanchez-Ramos, L. et al. (2009) Obstet. Gynecol. 114, 631.
3. Ness, A. et al. (2007) Am. J. Obstet. Gynecol. 197, 426.e1.
4. Alfirevic Z. et al. (2007) Ultrasound Obstet. Gynecol. 29, 47.
5. Lucovnik, M. et al. (2013) Am. J. Obstet. Gynecol. 209, 217.e1.
6. PartoSure Test Instructions for Use. QIAGEN, 2018.
7. American Hospital Association (AHA). US Birthing Hospital Data, 2016.
8. Wing et al. (2017) Obstet Gynecol. 130, 1183-91.